Health Condition 1: R688- Other general symptoms and signs Health Condition 2: K318- Other specified diseases of stomach and duodenum Health Condition 3: J988- Other specified respiratory disorders
Conditions
Interventions
Intervention1: Rocuronium as a muscle relaxant for intubation in neonates undergoing emergency surgery: Rocuronium will be given intravenously in the dose of 0.45mg/kg to achieve muscle relaxation for
Sponsors
Vardhman Mahavir Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Term neonates (0-1 month of age), American Society of Anesthesiologists (ASA) Grade 1 and 2, of either sex, undergoing emergency surgery under general anaesthesia requiring orotracheal intubation
Exclusion criteria
Exclusion criteria: 1. Neonates with anticipated difficult airway 2. Congenital syndromes involving head, neck and cardiovascular system 3. Raised intracranial pressure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate intubating conditions with rocuronium(0.45mg/kg) in neonates and compare it with succinylcholine (2mg/kg)Timepoint: Assessment of intubating conditions will be done at the time of intubation using the Goldberg scale | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate recovery time with rocuronium (0.45mg/kg) in neonates at the end of surgeryTimepoint: Recovery time will be measured by time to reversal and time to extubation. Time to reversal: Last skin suture to administration of reversal agents. time to extubation: Last skin suture to time of extubation. Neuro-muscular monitoring and time to achieve TOF ratio greater than 0.7, TOF ratio greater than 0.9 after skin closure will also be noted. | — |
Countries
India
Contacts
Public ContactVanya Chugh
Vardhman Mahavir Medical College and Safdarjung Hospital
Outcome results
None listed