Health Condition 1: G431- Migraine with aura
Conditions
Interventions
Intervention1: Propranolol, Amitryptyline, Sodium Valproate, Levocetirizine: T.Propranolol 40mg/T. Amitriptyline 25mg/T. Sodium Valproate 200mg
They can be given either as single or in combination the
Sponsors
Madras medical college
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with Migraine headache as per ICHD-3 criteria Patients fulfilling the criteria for the prophylaxis of Migraine Age group of 18-60 years of age Sex- Both male and female Patients who are willing to participate in this study
Exclusion criteria
Exclusion criteria: Patients with headache other than migraine Patients with complicated migraine like ophthalmic, hemiplegic or migraine with brainstem aura Patients with H/O severe drug allergy Patients with H/O severe co-morbidities like hypertension, Coronary artery disease, uncontrolled Diabetes Mellitus, thyroid disease, renal or liver disease, asthma. H/O any drug abuse or drug dependence Patients with H/O any psychiatric illness Pregnant ladies, lactating mothers and children less than 18 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| End points of the study1.Proportion of patients with 50% reduction in frequency of attacks at the end of 3rd month of the study Timepoint: At 3rd month of study | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the reduction in frequency and severity of pain intensity at the end of 6th month of the study To observe for any adverse effect with study drugTimepoint: At 6 months of study | — |
Countries
India
Contacts
Public ContactDr Chenthamarai
Institute of Pharmacology, Madras Medical College
Outcome results
None listed