Health Condition 1: H500- Esotropia
Conditions
Interventions
Intervention1: Botulinum toxin injection: PREPARATION OF BOTOX INJECTOIN
1ml normal saline is mixed with 50IU botulinum injection in order to prepare 5IU/0.1ml.
DOSAGE
Botox injection from 2.5 IU I t
4IU-esotropia 35-40pd
5IU-esotropia 45-50pd
6IU-esotropia 50-60pd
7-7.5 IU-esotropia 60pd
MODE OF ADMINISTRATION INJECTION
Both injection and surgery will be performed under general anesthesia (laryngeal mask). Proper perioperative pain management and social suppor
Sponsors
Post Graduate of Medical Sciences and Research
Eligibility
Inclusion criteria
Inclusion criteria: i. esotropia consistent with the diagnosis of Infantile Esotropia ii. Constant deviation of 20 prism dioptres (PD) or more iii. Age
Exclusion criteria
Exclusion criteria: 1. Horizontal muscle surgery performed prior to treatment. 2.Persistent severe amblyopia in one eye. 3. significant developmental delay or neurologic abnormalities 4. accommodative esotropia 5. oblique muscle overaction, presence of nystagmus, and dissociated deviations nystagmus 6.Fixation preference/ amblyopia 7. presence of vertical deviation 8. Children with previous or anticipated airway problems 9. Known drug sensitivity 10. Denial of parents to give consent for the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of percentage of success in botulinum toxin group with percentage success in early surgery groupTimepoint: 1week,1month,3months and 6months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Occurrence of timing of development of associated findings (eg dissociated vertical Deviation, superior oblique overaction, Inferior oblique overaction, A- V pattern present pre-operatively or develop during follow up) 2. Analysis of factors resulting in failure of botox injection Timepoint: 6 months follow-up from last intervention | — |
Countries
India
Contacts
Public ContactShweta Chaurasia
PGIMER
Outcome results
None listed