Health Condition 1: S818- Open wound of lower leg
Conditions
Interventions
Intervention1: Autologous platelets rich plasma: autologous PRP from the department of Transfusion Medicine, KGMU, Lucknow from autologous donor
Control Intervention1: Prolotherapy (25% dextrose solut
Sponsors
King Georges Medical University
Department of Transfusion Medicine
Eligibility
Inclusion criteria
Inclusion criteria: Patients giving written consent will be taken, Patient in the age group of 40 to 70 years. Knee osteoarthritis grade I & II (According to Kellgren et al classification scale)
Exclusion criteria
Exclusion criteria: Patients not giving informed consent, Knee osteoarthritis grade III to IV (According to Kellgren et al classification scale), Patients with rheumatoid arthritis or hemophilia, previous history of knee surgery, drug or alcohol addiction, and use of anticoagulant or nonsteroidal anti-inflammatory drugs (NSAIDS) in previous 7 days.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| ï?§ Followup will be done through OPD visits and regular mobile communication to ask regarding pain relief until 24 week and grading pain relief with respect to VAS and WOMAC scoreTimepoint: 24 week and grading pain | — |
Primary
| Measure | Time frame |
|---|---|
| ï?§ After injection patient will be offered acetaminophen tablets to use as needed for up to 1 week and advise knee rest for 2 -4 days with progressive resumption of routine activity over 1 month ï?§ They will be discouraged from using NSAIDS and start new therapies for their OA during study period Timepoint: VAS & WOMAC Score at 1 week, 1month, 3months & 6months. | — |
Countries
India
Contacts
Public ContactProf Sarita Singh
King Georges Medical University Lucknow
Outcome results
None listed