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Observational study to describe disease characteristics, treatment patterns, treatment-related outcomes for Chronic Lymphocytic Leukemia (CLL) patients.

A Multicenter Retrospective Study to understand the clinical characteristics, treatment pathway and resource utilization for patients with chronic lymphocytic leukemia. - CREEK Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/11/038192
Enrollment
1250
Registered
2021-11-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C919- Lymphoid leukemia, unspecified

Interventions

None listed

Sponsors

AstraZeneca Pharma India Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Primary diagnosis of Chronic Lymphocytic Leukemia (CLL) 2. Initiated CLL treatment (including 1st line 2nd line or Subsequent lines of treatment) within the period between 01 June 2016 and 12 months before data collection For GCC pilot cohort patients: treatment naive CLL patients diagnosed between 01 June 2016, and 12 months before data collection 3. Available medical records at the participating site reflecting at least 12 months of follow-up after starting on treatment (except in the case of the participant death within one year following treatment initiation) 4. Provision of informed consent by the patient or next of kin/legal representative (for deceased patients at study entry unless a waiver was granted) according to local regulations 5. Adult male or female =18 years old at the time of diagnosis or according to the age of majority as defined by local regulations)

Exclusion criteria

Exclusion criteria: 1. Failure to meet one or more of the inclusion criteria. 2. Any diagnosis of B cell malignancies other than CLL. 3. Current or prior use of acalabrutinib treatment. 4. Currently previously receiving treatment in an interventional clinical trial at the time of entry into this study for indications CLL.

Design outcomes

Primary

MeasureTime frame
(1) Recording patient characteristics. (2) Recording disease characteristics.Timepoint: one-time

Secondary

MeasureTime frame
(1) Recording the treatment patterns. (2) Recording the treatment-related outcomes.Timepoint: one-time

Countries

Australia, India

Contacts

Public ContactMr Amit Kumar

AstraZeneca Pharma India Ltd

drupad.hs@astrazeneca.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026