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Comparing the effects of two drugs, Dexmedetomidine and Magnesium Sulphate, on the Blood Pressure and Pukse rate changes that occur during Laparoscopic surgeries

Comparative study of hemodynamic changes with dexmedetomidine versus magnesium sulphate as adjuncts during anaesthesia in laparoscopic surgeries ââ?¬â?? a double blinded randomised study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/038123
Enrollment
64
Registered
2021-11-18
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: IV Dexmedetomidine : IV Dexmedetomidine 1 mcg/kg in 100 mL normal saline over 15 mins Intervention2: IV MAGNESSIUM SULPHATE: IV Magnessium Suphate 50mg/kg in 100 mL over 15 min Contro

Sponsors

Chettinad Hospital And Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: asa grade 1 and 2 elective and emergency laparoscopic surgeries

Exclusion criteria

Exclusion criteria: morbid obesity pregnant woman renal or hepatic dysfunction cardiovascular insufficiency

Design outcomes

Primary

MeasureTime frame
hemodynamic response of two drugs during intubation and CO2 insuffulationTimepoint: At baseline. Intubation response : Immediately after intubation(T0) 1 mintue after intubation (T1) 3 mintues after intubation (T3) 5 minutes after intubation (T5) Before insuffulation 1 minute after CO2 insuffulation (C1) 3 minutes after CO2 insuffulation (C3) 5 minutes after CO2 insuffulation (C5) Every 10 minute intraoperative monitoring—

Secondary

MeasureTime frame
hemodynamic response of two drugs during extubation and postoperative sedation score of patientTimepoint: 5 minutes post extubation—

Countries

India

Contacts

Public ContactProf Dr Anand S

Chettinad Hospital and Research Institute Kelambakkam

dranandmurugan@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026