Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous saline: After giving SAB with 2 mL (10 mg) of 0.5% hyperbaric bupivacaine and 0.5 mL (25 �¼g) fentanyl with a 27 g spinal needle or CSE set 18/27, intravenous saline will
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Patients of age 20-60 years, either sex, American Society of Anesthesiologists (ASA) physical status I and II undergoing surgery (min duration of 90min) under SAB or combined spinal epidural anesthesia (CSEA) will be enrolled for the study.
Exclusion criteria
Exclusion criteria: Patients with any known allergy to study drugs, contraindication for central neuraxial block, obesity (body mass index, [BMI] >35 kg/m2), neurological or psychiatric disease on concurrent medication and refusal will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare mean BIS score after Sub arachnoid block with bupivacaine (H) +fentanyl with and without intravenous midazolamTimepoint: BIS score will be assessed every 15 minutes up to 90 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare 1) haemodynamic parameters in both groups Timepoint: BIS will be recorded every 15 min during the study by a blinded research assistant. Other monitoring include electrocardiography, heart rate, automated blood pressure, pulse oximetry and respiratory rate at every 15min.Snoring will also be noted. | — |
Countries
India
Contacts
Public ContactDr Ummul Fabeena Mangaladan
AIIMS, New Delhi
Outcome results
None listed