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Aesthetic efficacy with oral premedication

The efficacy of oral premedication of NSAID on the anesthetic success of mental incisive nerve block in mandibular premolars with symptomatic irreversible pulpitis: A randomized clinical trial. - MIKE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/038115
Enrollment
102
Registered
2021-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Oral premedication with 10mg of ketorolac: Oral premedication with 10mg of ketorolac . Mental nerve incisive nerve block will be administered using a cartridge of 4% articaine with 1:10

Sponsors

Meenakshi academy of higher education and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with active moderate sharp spontaneous pain ( ï?³ 54 mm in Heft-Parker Visual Analog Scale (HP VAS)) or pain stimulated with hot or cold with lingering response even after removal of the stimulus with pain on biting or chewing in mandibular premolars 2. No evidence of periapical changes in radiographs (Periapical Index 3. Positive response to electric pulp testing (EPT) as well as a lingering response of more than 10 seconds to cold test (ethyl chloride spray).

Exclusion criteria

Exclusion criteria: 1. Teeth with crown/root fractures 2. Teeth with necrotic pulps following access cavity preparation 3. Patients with a lesion or swelling (periapical index > 2) (Ã?rstavik et al. 1986) at the site of injection. 4. Acute or chronic apical abscess. 5. Teeth with open apices 6. Compromised periodontium 7. Patients with any systemic diseases (American Society of Anesthesiologists Class II or higher) 8. Patients having history of allergy to local anesthetic solutions or any of the experimental drugs 9. Patients who could not interpret the HP VAS 10. Patients on long term medications that influenced pain threshold, analgesics, steroids and / or antibiotics in the recent past 24 hours. 11. Patients with a history of drug abuse 12. Patients who were unable to give informed consent

Design outcomes

Primary

MeasureTime frame
Efficacy of oral pre-medication on success of articaine mental incisive nerve block symptomatic in irreversible pulpitisTimepoint: lip anaesthesia, pulpal anaesthesia, access cavity preparation, instrumentation

Secondary

MeasureTime frame
Duration of lip & pulpal anesthesia and Adverse effect / post injection pain evaluationTimepoint: After the procedure, the patient will be called for a review the next day to assess the paresthesia and pain on injection site assessment

Countries

India

Contacts

Public ContactNandini Suresh

Meenakshi academy of higher education and research institute

nandini_80@hotmail.com9884292850

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026