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Diagnostic Challenges of Scrub typhus and Leptospirosis

Cross reactivity or Co-Infection of Scrub typhus & Leptospirosis: A Diagnostic Dilemma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/11/038107
Enrollment
345
Registered
2021-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A279- Leptospirosis, unspecified Health Condition 2: A753- Typhus fever due to Rickettsia tsutsugamushi

Interventions

None listed

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult In patients of both gender Fever more than or equal to 38°C for less than 14 days suspected to be leptospirosis or scrub typhus by treating physician

Exclusion criteria

Exclusion criteria: Pediatric patients Patients admitted to hospital with non-infectious etiology Known malignancy / immune-compromised conditions Unable to provide consent / unavailability of legally authorized representative

Design outcomes

Primary

MeasureTime frame
Four fold increase in antibody titers of scrub typhus and leptospirosis in convalescent sampleTimepoint: Day 14 of Illness—

Secondary

MeasureTime frame
Recovered / Recovering/ succumbedTimepoint: At the time of discharge—

Countries

India

Contacts

Public ContactSeshasai Kameswara Kiran Chunduru

Kasturba Medical College

kavitha.saravu@manipal.edu

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026