A clinical trial comparing the effect of two drugs namely dexmedetomidine and ketamine through nebulization given prior to surgery in children

COMPARISON OF PREMEDICATION WITH NEBULISED DEXMEDETOMIDINE AND KETAMINE AS PREMEDICATION IN CHILDREN

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/11/038096

Enrollment

Registered

2021-11-17

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine : Nebulized dexmedetomidine (2Âµg/kg body weight) diluted with 4ml 0.9% normal saline given as premedication in a group of children undergoing elective surgery, named a

Eligibility

Inclusion criteria

Inclusion criteria: Age group:3 to 10 years Elective surgery under general anaesthesia. American society of Anaesthesiologistâ??s grade I and grade II Normal airway

Exclusion criteria

Exclusion criteria: Active upper respiratory tract infection Patients with known allergy to study drug. Patients with significant organ dysfunction. Patients with cardiac dysrhythmias, congenital heart disease Patients using psychotropic medication. Patients with intellectual disability.

Design outcomes

Primary

Measure	Time frame
Level of sedationTimepoint: Preoperative Baseline, 5minutes, 10 minutes, 20 minutes, 30 minutes, Intra operative at beginning of surgery	—

Secondary

Measure	Time frame
Parental separation Mask acceptance Recovery timeTimepoint: Parental separation and Mass acceptance - Preoperative period recovery time after end of surgery Recovery- postoperatively	—

Countries

India

Contacts

Public ContactKalwal Vijaya Laxmi

VMMC and Safdarjung Hospital

drvandanatalwar@gmail.com9811352251

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026