Skip to content

Vascular changes in retina in amblyopic eyes verse in healthy eyes

Microvascular Changes In Amblyopic Eyes Versus Healthy Eyes By Optical Coherence Tomography Angiography In Children

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/11/038090
Enrollment
60
Registered
2021-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H53-H54- Visual disturbances and blindness Health Condition 2: H53-H54- Visual disturbances and blindness

Interventions

None listed

Sponsors

Varsha Negi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients in the age group of 6 to18 years with strabismic and anisometropic amblyopia (difference of at least 2 lines in BCVA between 2 eyes) 2.Age and Gender matched patients referred to OPD for routine eye examination will be recruited as control eyes.

Exclusion criteria

Exclusion criteria: 1.Poor quality scans and un co-operative child. 2.Children with spherical refractive errors of +/- 5.00 diopters(D) or greater and cylindrical refractive errors of 3.00 diopters(D) or greater. 3.Children with poor fixation, nystagmus, eccentric fixation. 4.Ocular diseases viz. cataract, corneal opacities, uveitis, retinal pathology 5.History of intraocular surgery 6.History of any systemic condition that could alter the retinal microvasculature

Design outcomes

Primary

MeasureTime frame
1.Foveal Avascular Zone Measurements (mm square) 2.Macular Vessel density percentage of SCP scan 3.Macular Vessel density percentage of DCP scan Timepoint: Baseline

Secondary

MeasureTime frame
1.Central Macular thickness (�µm) 2.Peripapillary Retinal nerve fiber layer thickness (�µm) Timepoint: 1 year

Countries

India

Contacts

Public ContactVarsha Negi

Guru Nanak Eye Center

varshaengi96@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026