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Comparison of Amfresh gel and Chlorhexidine gel as an adjunct to scaling and root planing in periodontitis patients.

"Comparative evaluation of efficacy of combination of resveratrol, chitosan, neem and curcumin gel and Chlorhexidine gel as an adjunct to scaling and root planing (SRP) in patients with periodontitis- A randomised controlled clinical trial."

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/038043
Enrollment
45
Registered
2021-11-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: Z515- Encounter for palliative care

Interventions

Intervention1: Amfresh gel: Combination of Resveratrol, Chitosan, Neem & Curcumin Dose: 1% w/w of Resveratrol, Chitosan, Neem & 0.05 % w/w of Curcumin depending upon the depth of the pocket Frequency:

Sponsors

Dr Swapna Mahale
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient diagnosed with Generalised periodontitis stage 2 grade 2 currently unstable with no risk factor 2. Patients with persistent pocket depth of minimum 4 -6 mm having minimum of 2-3 sites. 3. Systemically healthy subjects.

Exclusion criteria

Exclusion criteria: 1. History of any previous periodontal therapy in the last 6 months. 2.Use of drugs such as antibiotics, anti-inflammatory, corticosteroids, chemotherapeutics or immunological modulators that might alter the expected response of the oral tissues. 3. Tobacco consumption in any form. 4. Systemic diseases influencing the periodontal disease. 5. Pregnant and lactating women. 6. Allergy to chlorhexidine and Resveratrol, Chitosan, Neem & Curcumin (Amfresh) gel

Design outcomes

Secondary

MeasureTime frame
Gingival Index (GI) (Loe and Silness, 1963) Sulcus Bleeding Index.(SBI)(Muhlemann H.R & Son,1971)Timepoint: Baseline, 1 month and 3 months.

Primary

MeasureTime frame
Plaque index (PI) (Silness J, Lo¨e H. 1964) Probing Pocket Depth (PPD) Relative Attachment Level (RAL)Timepoint: Baseline, 1 month and 3 months.

Countries

India

Contacts

Public ContactDr Ankita Katkurwar

MGVs KBH Dental College and Hospital

drsamahale@gmail.com9422764080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026