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Comparison of two different doses of intravenous ketamine (intravenous anesthetic agent) added to intravenous dexmedetomidine (sedative) for awake fibre optic nasotracheal intubation

Comparison of two different doses of intravenous ketamine added to intravenous dexmedetomidine for awake fibre optic nasotracheal intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/038037
Enrollment
60
Registered
2021-11-15
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: 8- Other Procedures

Interventions

Intervention1: Addition of intravenous ketamine to intravenous dexmedetomidine for awake fibre optic nasotracheal intubation: Intravenous ketamine at two different doses will be administered to the pa

Sponsors

Goa Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with predicted airway posted for surgery under general anaesthesia ASA grade I and II

Exclusion criteria

Exclusion criteria: 1.Uncooperative patient/inability to communicate effectively 2.Pregnant women or patients requiring rapid sequence induction 3.Cardiopulmonary disease, heart rate (HR) 4.Allergy to the drugs involved in the study 5.History of drug or alcohol abuse, and patients on long-term opioids or sedative medication 6.Contraindication for nasal intubation 7.Patients of difficult airway with impending airway obstruction

Design outcomes

Primary

MeasureTime frame
To assess time taken for intubation on administration of two different doses of intravenous ketamine added to intravenous dexmedetomidine for awake fibre optic nasotracheal intubationTimepoint: To assess time taken for intubation on administration of two different doses of intravenous ketamine added to intravenous dexmedetomidine for awake fibre optic nasotracheal intubation from the point of introduction of the bronchoscope into the nares of the patient until securing the nasotracheal tube at the level of carina (which will be confirmed by direct visualization of trachea and carina using bronchoscope and capnography to exclude esophageal intubation.

Secondary

MeasureTime frame
Assessing variation in following parameters ie heart rate, Systolic blood pressure, Diastolic blood pressure, Mean Arterial pressure, Oxygen Saturation during the procedure of awake fibreoptic bronchoscope guided nasotracheal intubation. Timepoint: At following points above parameters will be measured ,besides time taken to reach these points will also be recorded 1.After insertion of scope 2.Scope at nasopharynx 3.Scope at Glottis 4.After intubation 1min 5min

Countries

India

Contacts

Public ContactPratiksha Sutar

Goa Medical College

docpai@rediffmail.com7741866436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026