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Compare effect of two drugs in spinal anaesthesia, bupivacaine and levobupivacaine for cesarean section

Comparative study of intrathecal bupivacaine and levobupivacaine with fentanyl for cesarean section:A prospective, randomised controlled, double blinded study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/038035
Enrollment
60
Registered
2021-11-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Hyperbaric bupivacaine(0.5%): spinal anaesthesia drug Intervention2: HYPERBARIC BUPIVACAINE(0.5%) 1.8ml intrathecally: Bupivacaine provide fast onset but is more cardiotoxic and neuroto

Sponsors

Government Medical College Bhavnagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA physical status I & II who will undergo cesarean section under spinal anesthesia 2) Patients with height between 150-170 cms 3) Patients with weight between 50-80 kgs 4) Gestational age more than 37 weeks

Exclusion criteria

Exclusion criteria: 1) Patients who had contraindication to spinal anesthesia. 2) Clinically significant coagulopathy. 3) Allergy to local anesthetic. 4) Infection at injection site. 5) Patients with spine deformities. Patients with moderate aneamia (Hb <10gm %).

Design outcomes

Primary

MeasureTime frame
To compare the onset, peak, duration and regression of sensory and motor blockage in both groups. Duration of analgesia(First request for analgesic)Timepoint: 24 hour

Secondary

MeasureTime frame
Hemodynamic parameters (Pulse rate, systolic BP, diastolic BP, MAP, SpO2). Complications and adverse effects if any. Neonatal outcomeTimepoint: 24 hours

Countries

India

Contacts

Public ContactDr Shilpa Doshi

Government Medical College, Bhavnagar

drshilpadoshi@yahoo.in09428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026