Post-Operative Quality Of Life In Patients Undergoing Root Canal Therapy Using Various Final Irrigation Solutions

Evaluation Of Post-Operative Quality Of Life In Patients Undergoing Two Visit Root Canal Therapy Following Final Irrigation With Cold Saline Or Diclofenac Sodium Solution -A Prospective Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/11/038013

Enrollment

Registered

2021-11-12

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Diclofenac Sodium: Final irrigation with Diclofenac sodium Diclofenac Sodium Dose-25mg/ml route of administration:root canal of teeth-intracanal irrigation frequency:once(final irrigati

Eligibility

Inclusion criteria

Inclusion criteria: Teeth diagnosed with symptomatic or asymptomatic irreversible pulpitis with or without apical periodontitis (acute or chronic) Primary root canal treatment in fully matured mandibular molars Teeth with enough crown structure for adequate isolation

Exclusion criteria

Exclusion criteria: Presence of periapical and periodontal lesions Teeth with complex root anatomy, resorption, re-treatment and calcifications Patients with chronic systemic disease and pregnant patients Patients who received analgesics or antibiotics within the preceding 6 hours before the procedure.

Design outcomes

Primary

Measure	Time frame
Post-Operative Quality of Life(Difficulty in chewing, speaking, sleeping, carrying out daily functions, social relations and overall QoL) and post-operative pain will be evaluated after 24,48,72 hours and 7 days Timepoint: 24,48,72, hours and 7 days	—

Secondary

Measure	Time frame
Postoperative pain (mean and maximum pain) will be assessed through a visual analogue scale (VAS)Timepoint: 24,48,72, hours and 7 days	—

Countries

India

Contacts

Public ContactSIDHARTH SIVAKUMAR

Sri ramakrishna dental college

subhaanirudhan1@gmail.com9786078340

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026