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COMPARISON OF DIFFERENT DOSES OF NALBUPHINE AS AN ADJUVANT IN SPINAL ANESTHESIA IN LOWER ABDOMEN AND LOWER LIMB SURGERIES

COMPARISON OF DIFFERENT DOSES OF INTRATHECAL NALBUPHINE AS AN ADJUVANT TO 0.5% HYPERBARIC BUPIVACAINE IN SUB-ARACHNOID BLOCK IN LOWER ABDOMEN AND LOWER LIMB SURGERIES

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/038007
Enrollment
50
Registered
2021-11-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Spinal anesthesia: After painting and draping of the lumbar area, a 26G Quincke spinal needle will be introduced in L3-L4 intervertebral space. Free and clear flow of CSF will be confir

Sponsors

Dr Tavleen Kaur Brar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18 to 60 years of either gender. 2. ASA grade I and II. 3. Patients posted for elective lower abdomen and lower limb surgeries under spinal anaesthesia. 4. Weight of the patient being in normal range for that age and sex. 5. Patients who are not on any antihypertensive, anti-platelet, fibrinolytic or anticoagulant drugs. 6. Haemodynamically stable patients with normal laboratory investigations. 7. Patients who give informed consent and are willing to be a part of the study.

Exclusion criteria

Exclusion criteria: 1. Patients with pre-existing cardiovascular diseases (IHD, hypertension, valvular heart disease), deranged liver functions or renal functions. 2. Patients with any neurological or psychiatric disorders. 3. Patients with any contraindications for neuraxial block. 4. Patients posted for emergency procedures 5. History of allergy to any of the drugs being used under study 6. Unwilling patients.

Design outcomes

Primary

MeasureTime frame
Determine the 1-Optimum dose with quicker onset 2-Duration of sensory and motor block 3-Duration of analgesic effect 4-Side effects, if anyTimepoint: 0 secs, 3 mins, 5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins—

Secondary

MeasureTime frame
To study the 1-Onset time of sensory block 2-Onset time of motor block 3-Two segment regression time of sensory block 4-Duration of motor block 5-Duration of effective analgesia 6-To study their side effects if any Timepoint: T1-baseline T2-3mins, T3-5 mins, T4-10 mins, T5- 15 mins, T6 - 20 mins, T7 - 25 mins, T8 - 30 mins—

Countries

India

Contacts

Public ContactDr Smita Joshi

Dr DY Patil Medical College and Hospital, Pimpri, Pune

smitajoshi6@rediff.com9822053792

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026