Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: inhalational and intravenous dexmedetomidine: one group will receive nebulization of dexmedetomidine preoperatively another group will receive intravenous infusion of dexmedetomidine pr
Sponsors
AIIMS Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: ASA I and II Patients undergoing elective surgery under general anaesthesia requiring endotracheal intubation
Exclusion criteria
Exclusion criteria: 1.Anticipated Difficult laryngoscopy and intubation or more than one attempt for intubation taken. 2.Patient having cardiovascular dysfunction. 3.Pre-existing hepatic or renal impairment. 4.Pregnant patients. 5.Patient refusal for consent. 6.Allergic to Study Drug. 7.Uncontrolled Hypertensive 8.Patients with raised intracranial pressure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the Mean Arterial Pressure and Heart rate changes following laryngoscopy between the study groups.Timepoint: at laryngoscopy, just after intubation, 1, 5, 10 min following intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare preinduction hemodynamics and sedation following administration of Dexmedetomidine.Timepoint: 15 minutes following administartion of intravenous or inhalational dexmedetomidine in preoperative area;To compare the propofol consumption during induction among the studied groupsTimepoint: dose of propofol will be calculated after completion of laryngoscopy and intubation | — |
Countries
India
Contacts
Public ContactDr Priyanka Gupta
AIIMS RISHIKESH
Outcome results
None listed