Health Condition 1: L80- Vitiligo
Conditions
Interventions
Intervention1: Whole body NB-UVB therapy to whole body except for hand/feet covered with gloves: NB-UVB will be administered thrice weekly on alternate days. The starting dose will be on 200mJ/cm2or 7
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of non-segmental vitiligo with body surface area involved 10-50%. 2. Bilateral lesions over the acral parts (lesions on hands/feet). 3. Active disease defined by VIDA 4+, occurrence of new lesions, progression of existing lesions, Koebnerisation. 4. Age 12-60 years
Exclusion criteria
Exclusion criteria: 1. Patients of segmental Vitiligo. 2. History of previous phototherapy or other immunosuppressive treatment. (â??For patients using any local or systemic immunosuppressive therapy, a washout period of 8 weeks is requiredâ??). 3. Patients without acral lesions. 4. Contraindications to use of NB-UVB 5. Intake of phototoxic drugs 6. History of skin malignancy or any current pre-malignant condition. 7. Claustrophobia 8. Hepatic or renal dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Proportion of patients achieving VIDA 3+ from baseline VIDA score of 4+ in both groups at 12 weeks follow-up 2.Proportion of patients achieving 50% improvement from baseline limb specific VASI in both groups at 24 weeks of follow-up Timepoint: 4weekly for 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactAnish Thind
PGIMER, Chandigarh
Outcome results
None listed