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THIS STUDY IS MEANT FOR UNDERSTANDING EFFICACY OF INTRAVENOUS USE OF DEXAMETHASONE IN PROLONGING POST OPERATIVE ANALGESIA AFTER SPINAL ANAESTHESIA.

A RANDOMISED CONTROL TRIAL TO STUDY THE EFFICACY OF INTRAVENOUS DEXAMETHASONE IN PROLONGING POST OPERATIVE ANALGESIA AFTER SPINAL ANAESTHESIA IN LOWER LIMB AND LOWER ABDOMINAL SURGERY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/037979
Enrollment
88
Registered
2021-11-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Inj Dexamethasone: Intravenous Inj Dexamethasone 0.1mg/kg Single shot of Inj Dexamethasone will be given 45 minutes before spinal anaesthesia. Control Intervention1: Normal

Sponsors

Shree krishna hospital Karmsad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing lower limb or lower abdominal surgery, of more than 60 mins duration. 2. Age 18 to 70 years of either sex 3. All patients with fasting period of 6hrs to solids and 2hrs to liquids

Exclusion criteria

Exclusion criteria: 1.Absolute contraindication to spinal anaesthesia 2.Patients on steroid therapy or past history of medication with steroids in last 1 year 3. Diabetic patient with HbA1c of more than 8 4. Obese patient with BMI > 40 5. In patientâ??s where there will be use of adjuvants intrathecally along with local anaesthetic drug 6. Intraoperative blood loss of more than 20% 7. Pre-operative hemoglobin level less than 10mg/dl 8. Patients with infections (appendicitis, choleycystitis, perforation, peritonitis) 9. Patients with Raised CRP and total counts 10. Allergy to local anaesthetic drug 11. Severe spinal deformity 12. Patient with preexisting neurological deficit 13. Parturient undergoing LSCS 14. Post-partum cases undergoing Abdominal TL

Design outcomes

Primary

MeasureTime frame
To evaluate efficacy of IV dexamethasone in prolonging postoperative analgesia after spinal anesthesia.Timepoint: Post operatively for 24 hours

Secondary

MeasureTime frame
To study the effects of IV dexamethasone on - intraoperative hemodynamics incidence of nausea, vomiting and shivering perioperatively.Timepoint: Hours

Countries

India

Contacts

Public ContactYash Shrotriya

H M Patel centre for medical care and education

yash.shrotriya8359@gmail.com7405485276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026