Health Condition 1: G408- Other epilepsy and recurrent seizures
Conditions
Interventions
Intervention1: tVNS stimulation: Patients with refractory epilepsy with daily seizures will be recruited and connected to a device which has integrated ambulatory EEG and tVNS. The base tVNS stimulati
Sponsors
DAEPARTMENT OF SCIENCE AND TECHNOLOGY
Eligibility
Inclusion criteria
Inclusion criteria: 1)Refractory epilepsy 2) Seizure frequency of at least 1 per day in the preceding 1month 3) Cooperative for undergoing the ambulatory EEG and tVNS stimulation 4) Underwent VEEG and had identified ictal EEG pattern
Exclusion criteria
Exclusion criteria: 1) Uncooperative patients 2) Pregnancy 3) Lack of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The baseline mean seizure frequency per week, 1 week prior to the admission will be compared to the seizure frequency after the admission while on add on treatment with tVNS after a week for in patients and after at 12- 20 weeks for outpatientsTimepoint: Baseline mean seizure frequency per week vs 1 week (for inpatients) or 12- 20 weeks (for outpatients) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) tolerability 2) side effectsTimepoint: 1week (inpatients) 12-20 weeks(outpatients) | — |
Countries
India
Contacts
Public ContactRavindranadh Chowdary Mundlamuri
NIMHANS
Outcome results
None listed