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Relationship between vitamin-D, gum diseases and sex hormone levels in women

ASSOCIATION OF VITAMIN D IN PATIENTS WITH PERIODONTITIS AND POLYCYSTIC OVARIAN SYNDROME: A CROSS-SECTIONAL STUDY

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/11/037906
Enrollment
100
Registered
2021-11-10
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of periodontitis will be enrolled for the periodontitis group. Inclusion criteria for the periodontitis group will be as follows: (a) presence of at least twenty teeth; (b) periodontitis with a minimum of 40% of sites with a clinical attachment level (CAL) >=2 mm and probing depth (PD) >=4 mm and (d) presence of >=40% sites with bleeding on probing (BOP). Patients with a diagnosis of PCOS will be enrolled for the PCOS group. Inclusion criteria for the PCOS groups will be as follows: (a) PCOS diagnosis will be made based on history, clinical signs, physical examination, laboratory parameters, and ultrasound findings which will be performed by a gynaecologist and radiologist. The PCOS diagnosis was based on the 2003 Rotterdam criteria. The control group consists of healthy women matched for age, no drugs are taken, no sites with PD >=4 mm or CAL >=4mm and with regular menstrual cycles without clinical or biochemical hyperandrogenism or PCO.

Exclusion criteria

Exclusion criteria: 1.Use of tobacco in any form 2.Use of oral contraceptives in the past 6 months 3.Treatment to periodontal disease in the past 6 months 4.No history of systemic disease 5.Pregnant women 6.History of malignancy or osteoporosis 7.Prophylactic antibiotics for dental procedures in the past 6 months.

Design outcomes

Primary

MeasureTime frame
To evaluate the association between serum vitamin D levels, periodontitis, and PCOS in patients with periodontitis and with PCOS.Timepoint: one time

Secondary

MeasureTime frame
To determine weather vitamin D levels have an impact on PCOSTimepoint: one time

Countries

India

Contacts

Public ContactSABBASANI DURGA SAAHITHI

Narayana dental college and hospital

sreenivasnagarakanti@gmail.com8333842124

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026