Use of sodium hypochlorite as sub gingival irrigant in periodontitis patients

CLINICAL AND MICROBIOLOGICAL EFFECT OF 0.25% SODIUM HYPOCHLORITE AS SUB GINGIVAL IRRIGANT IN CHRONIC PERIODONTITIS PATIENTS - A PILOT STUDY

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/11/037875

Enrollment

Registered

2021-11-08

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: saline: Group II( Control group): Subgingival irrigation with saline Duration:1 year Control Intervention1: 0.25% SODIUM HYPOCHLORITE AS SUB GINGIVAL IRRIGANT: Group I( Test group): Sub

Eligibility

Inclusion criteria

Inclusion criteria: 1. Minimum of 10 natural teeth present with at least two teeth with probing depth of 5- 6mm in chronic Periodontitis patients. 2. Clinical attachment loss of 1-2mm irrespective of age and gender. 3. Apparently healthy

Exclusion criteria

Exclusion criteria: 1. Patients who are under medication 2. Smokers 3. Pregnancy and lactating mother 4. Patients who received periodontal treatment in last 6 months 5. Patients who are unable to perform routine oral hygiene procedure

Design outcomes

Primary

Measure	Time frame
To assess and compare the clinical parameters in chronic periodontitis patients in both groups 2. To identify putative periodontal pathogens like Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia in Subgingival microbiologic samples in both groups.Timepoint: At two weeks interval for 3 months	—

Secondary

Measure	Time frame
To compare clinical and microbiological effects of sodium hypochlorite and saline as subgingival irrigantTimepoint: At two weeks interval for 3 months	—

Countries

India

Contacts

Public ContactAnumala Deepa

Sibar Institute of Dental Sciences

anumala.deepas@gmail.com9618501146

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026