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To compare three different doses of dexmedetomidine in patients undergoing awake fibreoptic intubation

PROSPECTIVE RANDOMIZED COMPARATIVE STUDY BETWEEN THREE DIFFERENT DOSES OF DEXMEDETOMIDINE ON INTUBATION CONDITIONS IN AWAKE NASOTRACHEAL FIBREOPTIC BRONCHOSCOPY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/037832
Enrollment
150
Registered
2021-11-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Fibreoptic Nasotracheal Intubation: Intubation of Difficult airway patients with inadequate mouth opening with fibreoptic bronchoscopy Control Intervention1: Dexmedetomidine: There will

Sponsors

DY Patil Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 All patient giving consent 2 Patient undergoing elective oro-maxillo-facial and oral malignancy surgeries 3 Patients >18 years or 4 Patients of either sex 5 ASA grade I and II

Exclusion criteria

Exclusion criteria: 1 Patients not consenting 2 Patient with coagulopathies or on anticoagulants 3 Nasal mass or Adenoids 4 Patients with severe renal, hepatic, respiratory or cardiac diseases, infection at the site of the block, pregnancy and neuromuscular disorders 5 Patients with any known allergy to dexmedetomidine 6 Patients with any contraindication to dexmedetomidine 7 Lack of cooperation or effective communication

Design outcomes

Primary

MeasureTime frame
To compare between three different doses of dexmedetomidine for sedation on intubation condition in awake nasotracheal fiberoptic intubation. The primary objective is to compare between three groups: Intubation score, patientsâ?? tolerance, 3-point assessment score immediately after nasotracheal intubation, hemodynamic parameters and incidence of oxygen desaturation if any. Timepoint: To compare pre infusion, 5 mins after infusion, 10 mins after infusion, pre intubation, during intubation and post intubation

Secondary

MeasureTime frame
Secondary objective is to observe side effects of drug, if anyTimepoint: 1.5 years

Countries

India

Contacts

Public ContactSanya Arora

DY Patil Hospital

drbgovardhane@gmail.com9027011111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026