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relative adrenal insufficiency in chronic liver disease

To study Relative Adrenal Insufficiency in Patients with Chronic Liver Disease (CLD) at Tertiary care Hospital (AIIMS) of Central India: A Prospective, Interventional (diagnostic), open label study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/037808
Enrollment
50
Registered
2021-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K746- Other and unspecified cirrhosis ofliver

Interventions

Intervention1: injection Synthetic adrenocorticotropic hormone 250 microgram: Blood samples will be taken to measure basal plasma cortisol levels at 0 minutes than at 30 and 60 minutes after synthetic

Sponsors

AIIMS Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-100 years 2. All patients diagnosed case of liver cirrhosis 3. Willing for admission 4. Who give consent for participation in the study.

Exclusion criteria

Exclusion criteria: 1. Patients on any type of steroids therapy and has continued till visit in emergency. 2. Prior enrolment in study 3. Medico legal cases 4. Patients who are diagnosed after admission 5. Only those Co-morbid condition which can alter the cortisol values like Patient on ketoconazole therapy, adrenalectomy, adrenal malignancy or adenoma.

Design outcomes

Primary

MeasureTime frame
mortalityTimepoint: 2 years—

Secondary

MeasureTime frame
disease associated complicationTimepoint: 2 years;duration of hospital stayTimepoint: 2 years;quality of lifeTimepoint: 2 years—

Countries

India

Contacts

Public Contactpankaj kumar kannauje

AIIMS, Raipur

drpankajkannauje@aiimsraipur.edu.in09752696488

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026