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A study to determine the dose of dexmedetomidine that can effectively prevent shivering after cesarean section with minimal side effects

To compare the efficacy of two different doses of IV dexmedetomidine for controlling post-operative shivering in women undergoing caesarean delivery under spinal anaesthesia: a prospective, randomized, double blind, parallel group, controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/037798
Enrollment
80
Registered
2021-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: IV Dexmeditomidine 20 micrograms: After the delivery of the baby and once the surgeon confirms adequate uterine tone and rules out excessive blood loss IV dexmeditomidine 20 microgram

Sponsors

Koldinne Jagadeeswara Reddy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Parturients with BMI 18-35kg/m2 undergoing caesarean delivery under spinal anaesthesia

Exclusion criteria

Exclusion criteria: • Patients refusal • Allergy and contraindication to the study drug (Dexmedetomidine) • Patients belonging to ASA grade III and above. • BMI 35kg/m2 • Twin / multiple pregnancy • History of chronic nausea or itching /pruritis during pregnancy • Psychiatric and mentally retarded patients

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of two different doses of IV dexmedetomidine i.e., 10µg and 20µg for reducing shivering in women undergoing caesarean delivery under spinal anaesthesia based on patient and observer rated scores taken at 30 and 60 min after arrival in the PACU compared with that of baselineTimepoint: 30 minutes and 60 minutes—

Secondary

MeasureTime frame
To study the side effects of dexmedetomidine (if any) like nausea/vomiting, pruritus, dry mouth and sedation postoperatively in the PACU for 60 min.Timepoint: for 60 minutes continuously—

Countries

India

Contacts

Public ContactKoldinne Jagadeeswara Reddy

AIIMS Raipur

drsaritaramchandani@gmail.com9424204244

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026