Comparison between two drug for reducing cardiovascular response for pneumoperitoneum in laparoscopic surgery

A comparative study of Dexmedetomidine and Magnesium sulphate for attenuation of hemodynamic responses to pneumoperitoneum in patients undergoing laparoscopic surgeries

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/11/037795

Enrollment

110

Registered

2021-11-03

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Dexmedetomidine: 1 microgram per kg body weight bolus followed by 0.4microgram per kg body weight per hour infusion. Control Intervention1: Nil: Nil Control Intervention2: magnesium sul

Eligibility

Inclusion criteria

Inclusion criteria: Patient belonging to ASA 1 and 11 Age group 18 to 50 years Patient undergoing elective laparoscopic surgeries lasting up to 2 hours

Exclusion criteria

Exclusion criteria: Patient refusal Known allergy to study drug History of hypertension, cardiovascular diseases,cerebrovascular diseases, chronic kidney diseases, diabetes mellitus and liver disorders Patient with serum electrolyte disturbances Patient with Brady arrhythmias

Design outcomes

Primary

Measure	Time frame
Attenuation of haemodynamic responsesTimepoint: just before creating pneumoperitoneum to deflation of pneumoperitoneum	—

Secondary

Measure	Time frame
extubation responsesTimepoint: at the time of extubation;extubation timeTimepoint: from stoppage of inhalation agent to the time extubation	—

Countries

India

Contacts

Public ContactDr BALA SUBRAMANYA H

Vijayanagar Institute of Medical Sciences

mukundeati@gmail.com7411442283

Outcome results