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A study to compare two different doses of Magnesium sulphate on heart rate,blood pressure,central venous pressure in patients undergoing laparoscopic surgery.

A comparative study of different doses of Magnesium sulphate on hemodynamic changes in patients undergoing laparoscopic surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/11/037788
Enrollment
90
Registered
2021-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium Sulphate: 30 mg/kg of body weight in 100 ml NS given over 10 minutes, after induction of anaesthesia before creation of pneumoperitoneum Control Intervention1: Magnesium sulph

Sponsors

Indira Gandhi Institute Of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (1) ASA physical states 1 and 2 (2)Patients undergoing laproscopic surgery with carbon dioxide pneumoperitoneum

Exclusion criteria

Exclusion criteria: (1)Patients refusal to participate (2)Patients on concomitant antihypertensive (3)Patients with unstable blood pressure ( hypertension or hypotension) ,cardiac dysfunction(NYHA grade 3 and 4),morbid obesity, severe renal,hepatic or endocrine dysfunction.

Design outcomes

Primary

MeasureTime frame
To assess the hemodynamic parameterTimepoint: at initiation of pneumoperitoneum and at 5 minutes,10 minutes,15 minutes and 20 minutes after pneumoperitoneum and at 10 minutes after exsufflation.

Secondary

MeasureTime frame
To assess the extubation time,incidence of post operative pain,shivering and other side effects of drug Timepoint: At extubation and 5 and 20 minutes after extubation.

Countries

India

Contacts

Public ContactDr Bibha Kumari

Indira Gandhi Institute Of Medical Sciences

drskritu@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026