Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis Health Condition 3: K808- Other cholelithiasis
Conditions
Interventions
Intervention1: Dexmedetomidine nebulisation: Dexmedetomidine Nebulisation at a dose of 1 µg/kg (mixed with saline to a total volume of 5 ml).
Control Intervention1: Nebulisation with 5 ml normal sali
Sponsors
Department of anesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: Patients having ASA physical status I and II ,aged between 18 and 60 years with normal airway belonging to both the genders undergoing elective laparoscopic cholecystectomy surgery under general anaesthesia with endotracheal intubation
Exclusion criteria
Exclusion criteria: 1.Patients who are not consenting for the study 2.Predicted airway difficulty 3.Pregnancy 4.Renal failure 5.Uncontrolled hypertension 6.Seizure disorders 7.Patient on anti-depressants/anti-psychotics 8.Patients with a poor cardiopulmonary reserve and 9.Body mass index (BMI) >30 kg/m2 10.Other coexisting Medical disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of nebulised dexmedetomidine premedication in patient undergoing laparoscopic cholecystectomy surgeries in general anaesthesia regarding - 1.Attenuation of perioperative haemodynamic stress response. 2.Anaesthetic agent sparing effect 3.Side effects, if anyTimepoint: Baseline before nebulisation ,in premedication room after nebulisation,in premedication room Before premedication in OT After induction just before intubation Immediately after intubation 3 min, 5 min, after intubation At surgical Incision Just after insufflation 15 min after insufflation and at every 15 min thereafter At Exsufflation Just after Reversal | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects, if anyTimepoint: any time intraoperative,postoperative | — |
Countries
India
Contacts
Public ContactNAVEEN KUMAR
RNT MEDICAL COLLEGE
Outcome results
None listed