Health Condition 1: C73- Malignant neoplasm of thyroid gland
Conditions
Interventions
None listed
Sponsors
Amrita Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: All patients diagnosed with differentiated thyroid carcinoma, who have undergone surgical management and with a minimum 5 year period follow up will be included in our study. Patients with elevated thyroglobulin levels ( >2ng/ml) and a negative iodine scintigraphy will be included into the ââ?¬Å?TENISââ?¬? group and patients showing direct correlation between Tg levels and iodine scintigraphy (elevated Tg with positive scan and undetectable Tg with negative scan) will be included into the ââ?¬Å?without TENISââ?¬? group
Exclusion criteria
Exclusion criteria: Patients with iodine scan identifying lesions in the setting of elevated thyroglobulin will be excluded from the TENIS group. Patients with elevated anti Tg antibody ( > 30IU/L), who were not willing for radio iodine ablation and those not on regular follow up or lost on follow up within one year of diagnosis will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Serum Tg Level, Whole Body Iodine Scintigraphy, Radio Iodine Ablation TherapyTimepoint: 3- 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Distant MetastasisTimepoint: 1 year, 3 year, 5 year;Local recurrenceTimepoint: 1 year , 3 year , 5 year;Mean serum Tg LevelTimepoint: 6 months;Need for FDG PET scanTimepoint: 1 year, 3 year, 5 year;Need for Re-surgeryTimepoint: 1 year, 3 year, 5 year | — |
Countries
India
Contacts
Public ContactAshwin Vinod
Amrita Institute of Medical Sciences
Outcome results
None listed