Evaluation of magnesium sulphate gargle for post operative sore throat

Evaluation of magnesium sulphate gargle for post operative sore throat in patients undergoing general anaesthesia with endotracheal intubation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/10/037622

Enrollment

Registered

2021-10-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: nil: nil Control Intervention1: PREOPERATIVE MAGNESIUM SULPHATE GARGLES FOR POST OPERATIVE SORE THROAT: To evaluate the efficacy of pre-operative gargles with magnesium sulphate 20mg/kg

Eligibility

Inclusion criteria

Inclusion criteria: belonging to ASA physical status 1 and 2 undergoing laparoscopic surgery under general anaesthesia with endotracheal intubation.

Exclusion criteria

Exclusion criteria: 1) patients with difficult airway. 2) patients with a history of pre-operative sore throat , oral surgeries, asthma , diabetes, chronic obstructive pulmonary disease , head and neck surgeries. 3) patient with known allergies to study drug and rescue drugs. 4) duration of surgery 4 hours. 5) patient consuming non steroidal anti inflammatory drugs within 24hours prior to the surgery or on systemic / topical steroid therapy or taken steroid drugs within 5 days prior to surgery.

Design outcomes

Primary

Measure	Time frame
TO EVALUATE THE INCIDENCE AND SEVERITY OF POST OPERATIVE SORE THROAT IN PATIENTS RECEIVING PREOPERATIVE GARGLE OF MAGNESIUM SULPHATE 20MG/KG DILUTED UPTO 30ML WITH NORMAL SALINE UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA WITH ENDOTRACHEAL INTUBATIONTimepoint: AT 0hr, 2hr, 4hr and 24hr	—

Secondary

Measure	Time frame
To evaluate incidence and severity of cough and hoarseness of voice in patients receiving preoperative gargle with magnesium sulphate 20mg/kg diluted upto 30ml with normal saline .Timepoint: at 0hr, 2hr, 4hr and 24hr	—

Countries

India

Contacts

Public ContactDr Urvashi Mehra

VMMC AND SAFDARJUNG HOSPITAL

shruti.anaesth@gmail.com9212308441

Outcome results