A Clinical trial to study the effect of the drug Chanthirothaya Mathirai in management of patients having Rheumatoid Arthritis(Uthiravatha Suronitham)

Phase II Non-Randomized Open Clinical Evaluation of Siddha Medicine Chanthirothaya Mathirai for the management of Uthiravatha Suronitham (Rheumatoid Arthritis)

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/10/037553

Enrollment

Registered

2021-10-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M059- Rheumatoid arthritis with rheumatoid factor, unspecified

Interventions

Intervention1: CHANTHIROTHAYA MATHIRAI: 360 mg of Chanthirothaya Mathirai is administered twice a day with Indhuppu legiyam for 48 days Control Intervention1: NIL: NIL

Eligibility

Inclusion criteria

Inclusion criteria: Age limit of 20-55 years Anti Cyclic Citrullinated Peptide(AntiCCP)-5ml or more and RA positive H/O Morning stiffness for more than 1 hour Multiple joint involvement Symmetreical Arthritis Rheumatoid Nodules

Exclusion criteria

Exclusion criteria: H/O Rheumatic fever H/O Psoriatic Arthropathy H/O Reiters Arthritis H/O Systemic Lupus Erythematous H/O Sjogrens syndrome H/O Progressive Systemic Sclerosis H/O Any other serious systemic Illness Pregnant women, Lactating Mothers

Design outcomes

Primary

Measure	Time frame
Primary outcome is mainly assessed by reduction in clinical symptoms measured by Universal pain Assessment Scale(Visual Analogue Scale)Timepoint: 48 days	—

Secondary

Measure	Time frame
Secondary Outcome is assessed by comparing the safety parameters before and after treatmentTimepoint: 48 days	—

Countries

India

Contacts

Public ContactDr Sudhaadevi PV

Government Siddha Medical College

chittu758@gmail.com9444177230

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026