A Clinical Trial to study the mindfulness-based approach to exposure and response prevention to improve acceptability and outcomes.

Mindfulness-Based Exposure and Response Prevention in Individuals with Obsessive Compulsive Disorder: A Randomised Controlled Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/10/037545

Enrollment

Registered

2021-10-25

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F42- Obsessive-compulsive disorder

Interventions

Intervention1: MINDFULNESS BASED- EXPOSURE AND RESPONSE PREVENTION: Intervention package consist of Exposure and Response Prevention exercises (adopted from Foa, Yadin, & Lichner, 2012) and Mindfulnes

Eligibility

Inclusion criteria

Inclusion criteria: 1. Meet DSM-5 (American Psychiatric Association, 2013) diagnostic criteria for OCD based on the Mini International Neuropsychiatric Interview [MINI 7.0.0] 2. Participants should be stable on psychiatric medication for at least 3 months prior to consent 3. Participants with no plans for changing psychiatric medication during the study 4. Participants with mild to moderate severity of depression 5. Aged between 18-45 years and both genders 6. Able to understand, read and write Hindi or English

Exclusion criteria

Exclusion criteria: 1. People with the history of an identified organic cause for their OCD symptoms 2. Participants falling in ICD-10 (DCR) diagnostic criteria for a psychotic disorder, post-traumatic stress disorder (PTSD), substance abuse/dependence 3. Diagnosed with learning disability

Design outcomes

Primary

Measure	Time frame
Mindfulness based Exposure and response prevention in comparison to Exposure and response prevention would lead to greater improvements in OCD symptom severity at post-intervention.Timepoint: 12 weeks-Post Assessment 4 weeks- Follow up	—

Secondary

Measure	Time frame
MB-EX/RP in comparison to EX/RP will have greater improvemnts in depression symptom severity, mental wellbeing, mindfulness and obsessive-compulsive beliefs.Timepoint: 12 weeks- Post Assessment 4 weeks - Follow up	—

Countries

India

Contacts

Public ContactSHEIKH MOHAMMAD ASIF

Christ University, Bengaluru

mareena.wesley@christuniversity.in7760044688

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jul 17, 2026