Health Condition 1: O269- Pregnancy related conditions, unspecified
Conditions
Interventions
None listed
Sponsors
The National Institutes of Diabetes and Digestive and Kidney Disorders NIDDK
Boston University School of Public Health
Eligibility
Inclusion criteria
Inclusion criteria: � Mother must be a participant in the A-PLUS trial � Infant must be enrolled prior to discharge from the hospital after delivery � Family must be planning to remain in the Nagpur area for the next 12 months
Exclusion criteria
Exclusion criteria: � Infants with multiple congenital anomalies (e.g., cyanotic congenital heart disease, spina bifida, or other nervous system malformations) will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infant length (length-for-age z-score)Timepoint: at 24-hrs, 1-week, 6-weeks and 3, 6, 9 and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome TimePoints ââ?¬Â¢ Additional growth indicators (weight-for-age and weight-for-length z-scores, middle-upper-arm-circumference and head circumference)Timepoint: at 5 time points (24-hours, 1-week, 6-weeks and 3, 6, & 9 months;ââ?¬Â¢ Antibiotic levels in womenââ?¬â?¢s breastmilkTimepoint: at 5 time points (24-hours, 1-week, 6-weeks and 3, 6, & 9 months;ââ?¬Â¢ Infant GI microbiome indicators (alpha diversity, beta diversity, relative abundance of different taxa, metabolic capacity)Timepoint: at 5 time points (24-hours, 1-week, 6-weeks and 3, 6, & 9 months;ââ?¬Â¢ Maternal breastmilk and aereolar skin microbiome indicators (alpha diversity, beta diversity, relative abundance of different taxa)Timepoint: at 5 time points (24-hours, 1-week, 6-weeks and 3, 6, & 9 months | — |
Countries
India
Contacts
Public ContactDr Archana Patel India
Lata Medical Research Foundation
Outcome results
None listed