FindTrial
Sign In

To compare effect of oral pregabalin and lamotrigine on post operative analgesia

Comparative study of pre-emptive pregabalin and lamotrigine on post-op analgesia for adult patients undergoing major surgeries under general anaesthesia - preemptive Lamotrigine 100mg vs Pregabalin 150mg

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037524
Enrollment
60
Registered
2021-10-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Orally pregabalin or lamotrigine will be given 2hours prior to surgery: Drug will be administered orally 2hours prior to surgery Control Intervention1: Oral pregabalin and oral lamotrig

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: . With patients consent . Subjects included - 18-60 years of age of either sex . Patients undergoing major surgeries less than 3 hours under general anesthesia . ASA I and ASA II

Exclusion criteria

Exclusion criteria: . Patient refusal . Pediatric age group (0-17yrs age) . Emergency surgeries . Sepsis . ASA III and above . CNS disorders . Cardiac diseases . COPD and Chronic respiratory illnesses . Known Allergy to these drugs

Design outcomes

Primary

MeasureTime frame
Perioperative monitoring HR, SBP, DBP, SPO2, RR, ETCO2Timepoint: 30min,60min,90min,2hr,3hr,4hr,5hr,6hr,8hr,10hr,12hr,14hr,16hr,18hr,20hr,22hr,24hr postoperatively—

Secondary

MeasureTime frame
Post operative monitoring- HR, SBP, DBP, MAP, SPO2, VISUAL NUMERICAL PAIN SCALE, RAMSAY SEDATION SCALETimepoint: 30min, 1hr, 90min, 2hr, 3hr, 4hr, 5hr, 6hr, 8hr, 10hr, 12hr, 14hr, 16hr, 18hr, 20hr, 22hr, 24hr—

Countries

India

Contacts

Public ContactDr I Mohammed Arafath

ESIC MC and PGIMSR Chennai

gilang@rediffmail.com9884149429

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026