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A clinical trial to study the effect of nebulized lignocaine and ketamine in reducing incidence of postoperative sore throat

Comparison of the effects of nebulized Ketamine and nebulized Lignocaine in decreasing incidence of post-operative sore throat : A randomized control prospective study - ketlo

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037492
Enrollment
120
Registered
2021-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: lignocaine 4% nebulization: Group L will receive lignocaine 4% nebulization( 2ml lignocaine 4% + 3ml saline) 15 min prior to induction in pre op room. Intervention2: ketamine 50 mg: Gr

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with American Society of Anesthesiologists (ASA) class I or class II physical status.

Exclusion criteria

Exclusion criteria: 1. Patient refusal , 2. Pateints with ASA physical status III & IV, 3. History of allergic reactions to local anaesthetics or ketamine, 4. Patient with anticipated difficult intubation, 5. Duration of intubation more than 30s or more than 1 attempt of intubation, 6. Patients undergoing oral, head and neck surgeries, 7. Duration of surgery > 2hr

Design outcomes

Primary

MeasureTime frame
Incidence and severity of sore throat in first 24 hours of post operative periodTimepoint: Sore throat monitoring and grading will be done at 0,1, 2, 4, 8, 12, 16 and 24 hours post-extubation by an anaesthetist not aware of the group of patients

Secondary

MeasureTime frame
To report any complication or side effect due to nebulization of lignocaine and ketamine if seenTimepoint: Monitoring will be done at 0, 2, 4, 8, 12, and 24 hours post-extubation by an anaesthetist.

Countries

India

Contacts

Public ContactSwapnil Kumar Barasker

Sri Aurobindo Medical College and PG Institute

swapnilkbarasker@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026