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Assessing the effect of clonidine(antihypertensive drug) in reducing the increase in heart rate and blood pressure during electroconvulsive therapy

Efficacy of intravenous clonidine in attenuating hemodynamic response during modified electroconvulsive therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037481
Enrollment
40
Registered
2021-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Premedication with clonidine: Clonidine 2 mcg/kg diluted in 50 ml normal saline is administered intravenously over 15 minutes, 15 minutes before the procedure as premedication Control I

Sponsors

Vigneshwaran S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients undergoing modified ECT belonging to ASA class 1 and 2

Exclusion criteria

Exclusion criteria: Patients belonging to ASA class 3 and 4, patients with ischemic heart disease, cardiac arrythmias, uncontrolled hypertension, history of stroke within one year, renal and hepatic dysfunction

Design outcomes

Primary

MeasureTime frame
To determine the efficacy of premedication with intravenous clonidine in attenuating hemodynamic response ( Heart rate, Systolic, diastolic and mean blood pressures)Timepoint: baseline (just before premedication), just before induction of anesthesia, just before administration of ECT, and post ECT at 2, 4, 6, 8, 10, 15, 20, 30, 45 minutes and at 1, 1.5 and 2 hours

Secondary

MeasureTime frame
To determine the efficacy of premedication with intravenous clonidine in the prevention of post ECT agitation using Richmond agitation - sedation scaleTimepoint: Post ECT every 5 minutes upto 1 hour and then every 15 minutes during second hour

Countries

India

Contacts

Public ContactVigneshwaran S

Vinayaka Missions Kirupananda Variyar Medical College & Hospitals, Salem

drsvigneshwaran@gmail.com8826933957

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026