Health Condition 1: - Health Condition 2: I219- Acute myocardial infarction, unspecified
Conditions
Interventions
Intervention1: Coronary angiogram and Optical coherence Tomography findings: Optical coherence Tomography findings in heart attack patients with apparently normal/near normal angiogram
Intervention2:
Sponsors
Dr Louie Fischer
Eligibility
Inclusion criteria
Inclusion criteria: Patients fulfilling the MINOCA criteria according to the European Society of Cardiology guidelines and the American heart Association Scientific Statement will be included in the study. Criteria for AMI including troponin rise above the 99th percentile upper reference limit and corroborative clinical evidence of infarction according to the fourth universal definition of myocardial infarction, absence of obstructive CAD defined as no coronary artery stenosis > or equal to 50% in any potential infarct related artery on coronary angiography and no specific alternate diagnosis for the clinical presentation.
Exclusion criteria
Exclusion criteria: Prior history of AMI or CAD, coronary angioplasty or stenting, Severe renal failure (estimated glomerular filtration rate < 30 mi/min), systemic prothrombotic disease, current or previous presentation with heart failure, pregnancy, pulmonary embolism, aortic dissection. High troponin levels presumed due to non cardiac etiologies including sepsis, clinically diagnosed myocarditis, tokotsubo cardiomyopathy, coronary thromboembolism and extremely tortuous vessels (precluding OCT run) on coronary angiography.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To identify the presence of any coronary artery pathology 2. To assess morphological features of lesions 3. To study the association of coronary pathology with various known cardiovascular risk factorsTimepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| NoneTimepoint: None | — |
Countries
India
Contacts
Public ContactDr Louie Fischer
MOSC MCH Kolenchery
Outcome results
None listed