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IV dexmeditomidine prior to intubation

A comparative study between different doses of intravenous Dexmedetomidine in attenuation of pressor response to laryngoscopy and endotracheal intubation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037428
Enrollment
80
Registered
2021-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical Health Condition 4: O- Medical and Surgical Health Condition 5: O- Medical and Surgical

Interventions

Intervention1: Dexmeditomidine 1mcg and 0.5mcg: To compare and study the pressor response to laryngoscopy and endotracheal intubation with different doses of IV Dexmeditomidine Control Intervention1:

Sponsors

Dr Waseema Kabeer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18-60 yr of either sex. 2. ASA grade I and grade II. 3. Patients posted for elective surgeries under general anesthesia requiring intubation. 4. Hemodynamically stable patients having all routine investigations within normal limits. 5. Patients who give written informed consent and are willing to be part of the study.

Exclusion criteria

Exclusion criteria: 1. Patients refusal. 2. Patients with ASA physical status III and more. 3. Patients with any pre-existing cardiovascular disease. 4. Patients with h/o allergy to test drugs. 5. Patients posted for emergency surgeries. 6. Patients with difficult airway. 7. Patients with neurological disorders and muscle diseases.

Design outcomes

Primary

MeasureTime frame
To observe the attenuation of pressor response to laryngoscopy and endotracheal intubation with IV dexmedetomindineTimepoint: PRE SCOPE, AT THE TIME OF SCOPY, 0 MINS, 5 MINS, EVERY 5 MINUTES UPTO 2 HOURS, POST EXTUBATION VAS—

Secondary

MeasureTime frame
To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with intravenous Dexmeditomidine 1mcg/kgTimepoint: PRE SCOPE, AT THE TIME OF SCOPY, 0 MINS, 5 MINS, EVERY 5 MINUTES UPTO 2 HOURS, POST EXTUBATION VAS—

Countries

India

Contacts

Public ContactDr Smita Joshi

Dr. D.Y Patil medical college and hospital

smitajoshi6@rediffmail.com9822053792

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026