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Steroid In Esophageal Sticture

Efficacy of Intralesional Steroid Injection on Esophageal Stricture Dilatation in Children:A Randomized Controlled Trial - SIESD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037410
Enrollment
90
Registered
2021-10-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K228- Other specified diseases of esophagus

Interventions

Intervention1: Intralesional steroid injection ( Triamcinolone): Intralesional steroid injection 10 mg/0.5 ml in 4 quadrants will be given in stricture segment with esophageal stricture dilatation in

Sponsors

Chacha Nehru Bal Chikitsalaya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children having esophageal stricture and requiring more than three dilatation.

Exclusion criteria

Exclusion criteria: Long and Multiple Strictures Post Sclerotherapy Strictures

Design outcomes

Primary

MeasureTime frame
To compare number of dilatations in patients of benign refractory or recurrent esophageal stricture receiving intralesional steroid injection with dilatation or dilatation alone which will be measured as periodic dilatation index.Timepoint: After four sessions dilatation

Secondary

MeasureTime frame
- To compare the level of dysphagia and the childâ??s eating behaviour between the two groups. - To compare the effect of intralesional steroid injections on the luminal diameter and the stricture length between the two groups. - To evaluate a possible influence of comedication (eg Proton pump inhibitor) on stricture recurrence. - To compare complication rate (perforation and requirement of surgery) in two groups. Timepoint: six month

Countries

India

Contacts

Public ContactAnuradha Rai

Chacha Nehru Bal Chikitsalaya

anuradharai2@gmail.com91-8800674851

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026