Health Condition 1: O244- Gestational diabetes mellitus
Conditions
Interventions
Intervention1: metformin: to study the extent of glycemic control with the use of metformin in women with GDM
Route Oral
Dose According to Blood Sugar
Dose 500 mg to 2 gm
Control Intervention1: insu
Sponsors
AIIMS Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1.Pregnant women between 18-45 years of age. 2.Singleton pregnancies at 26-30 weeks of Period of gestation. 3.Pregnant women Diagnosed with GDM according to IADPSG criteria (International association of diabetes and pregnancy study group) who failed to control on MNT only.
Exclusion criteria
Exclusion criteria: 1.Contraindication to Metformin (Chronic Heart failure, Metabolic acidosis, Diabetic ketoacidosis, Severe Renal disease and pulmonary disease). 2.Medical Disorder (Chronic Hypertension, Type 1 and 2 Diabetes mellitus, Liver disease). 3.Fetal anomaly 4. Intra uterine fetal growth restriction. 5. With macrosomia and polyhydramnios 6. Fasting blood sugar =126 mg/dl and Post Prandial blood sugar = 200 mg/dl 7 . Preterm ruptured membrane. 8. Patient not giving consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess successful maternal glycemic control in Gestational Diabetes Mellitus after 2 weeks of starting the pharmacological treatment. Timepoint: from 24 weeks POG till 6 weeks postpartum | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To compare HBA1c in both the groups at 36-38 week of period of gestation. 2 .To compare the clinical evidence of macrosomia and polyhydramnios in pregnancies complicated by GDM on insulin or metformin. Timepoint: from 24 weeks POG till 6 weeks postpartum | — |
Countries
India
Contacts
Public ContactManisha Jhirwal
AIIMS, Jodhpur
Outcome results
None listed