Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: TOF Monitor: Time from the last dose of injection Vecuronium till recovery TOF ratio to 0.9 in Group A
Intervention2: TOF Monitor: Time from the last dose of injection Vecuronium till r
Sponsors
Dr D Y Patil Hospital and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing general anaesthesia Patients under ASA I and II Age between 18 to 60 years. Patients willing to sign the informed consent voluntarily
Exclusion criteria
Exclusion criteria: Pregnant females Patients with cognitive and mental disorders Patients with any neuromuscular disorders ASA III and above Patients with anticipated difficult intubation Surgery duration of more than 4 hours Surgeries in which either major blood loss/fluid shifts expected or occurs Surgeries of Head and neck Planned for awake extubations Patient in need of postsurgery intensive care admission Patient with body mass index >35 kg/m2 Patient with hepatic disease (liver enzyme value >50% normal value) Patient with renal insufficiency (serum creatinine >1.8 mg/dL) Patient with history of consumption of drugs known to affect neuromuscular transmission Any contraindications to neostigmine and/or atropine sulphate Patient with history of hypersensitivity or allergic to anaesthetic agent given Difficulty accessing the TOF measuring device in the ulnar nerve.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effect of neuromuscular transmission monitoring (train of four) on the requirement of muscle relaxant and recovery in patients undergoing general anaesthesiaTimepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To determine the total dose of muscle relaxant requirement for intubation 2)To determine the dose of intra-operative muscle relaxant requirement per hour 3)To observe the time required for the patient to respond to verbal commands after stopping of all the anaesthesia maintenance drugs 4)To observe the time required for extubation 5)To observe for any postoperative residual paralysisTimepoint: 5 hours | — |
Countries
India
Contacts
Public ContactDr Preeti Raj
Dr D Y Patil Hospital and Research Centre
Outcome results
None listed