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To Study effectiveness of 2 different medicines in preventing change in patient vitals both before and after inserting an airway device in patients taken for surgery

â??COMPARISON OF DEXMEDETOMIDINE-PROPOFOL VERSUS FENTANYL-PROPOFOL FOR INSERTION OF BLOCKBUSTER-LMA UNDER GENERAL ANAESTHESIA -A RANDOMIZED DOUBLE-BLINDED CLINICAL TRIALâ??

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037358
Enrollment
120
Registered
2021-10-18
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: using blockbuster-Laryngeal mask airway for blind intubation in General anesthesia cases: blind intubation via blockbuster intubating laryngeal mask airway in all 120 patients allocated

Sponsors

JHALAWAR MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) ASA grade I and II. b) Aged 18-50 years. c) MPG I and II d) Either gender undergoing general anaesthesia. e) Elective surgeries f) Weight- 50 -80 kg

Exclusion criteria

Exclusion criteria: a) Difficulty in understanding the study protocol/ denying consent b) History of sleep apnoea c) Known allergy to the study medication d) Bronchial asthma e) Respiratory or cardiac dysfunction f) Acute upper respiratory tract infection g) Renal, cerebral insufficiency h) Liver impairment and bleeding disorders i) Hiatus hernia, pregnancy, emergency surgeries j) Taking medications for psychiatric diseases k) Chronic or acute intake of sedative or analgesic drugs.

Design outcomes

Primary

MeasureTime frame
1.Monitoring of haemodynamic parameters, 2.ETCO2 and 3.SpO2 during insertion of deviceTimepoint: baseline vitals ,vitals before and after giving study drug , vitals every 1 min upto 30 mins intraop.

Secondary

MeasureTime frame
1.Quality of insertion : (a) Ease of insertion (b) Number of attempts (c) Time taken for insertion 2.Manoeuvres used for intubation 3. Peri- and post-operative complicationsTimepoint: starting from preop.baseline values, during performing procedure and hourly upto 24hours post.op

Countries

India

Contacts

Public ContactANUBHUTI JAIN

jhalawar medical college, jhalawar

dranubhutijain0@gmail.com8426887699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026