Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Control Intervention1: oral clonidine: Oral clonidine 150mcg 1 hour before surgery for attenuation of pressor response
Control Intervention2: Oral pregabalin: oral pregabalin 150mg 1hr before surgery
Sponsors
Dr Sathvika Pati
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients in age group of 18 to 60 years 2) Patients with ASA I and II 3) Hemodynamic stable patients 4) Patients posted for laparoscopic surgeries under general anesthesia 5) Patients willing to give consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1) Patients with known case of diabetes, cardiac, respiratory and renal disease. 2) Patients with anticipated difficult intubation 3) Patients on prolong antihypertensive drugs, sedatives and hypnotic drugs 4) Patients with known allergy to any anesthetic medication 5) Obese patient 6) Patients with ASA >II 7) Lack of patient consent .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) To observe perioperative hemodynamic stability during laryngoscopy and laparoscopy. Timepoint: 30 minutes , 1hr after premedication,1 minute, 3minute after intubation, start of pneumoperitoneum, 15 min ,30 min after CO2 insufflation , 15min after release of CO2 insufflation , extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To observe postoperative analgesia requirement, sedation.and To observe any side effects.Timepoint: Immediately after surgery , 1hr after surgery | — |
Countries
India
Contacts
Public ContactSathvika Pati
Dr. DY Patil Medical College and Hospital, Pimpri
Outcome results
None listed