Health Condition 1: K00-K95- Diseases of the digestive system
Conditions
Interventions
Intervention1: Gluten free diet: A gluten-free diet is a diet that excludes foods containing gluten. Gluten is a protein which is found in wheat, barley, rye and triticale (a cross between wheat and r
Sponsors
Dayanand Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Persistent GI symptoms (dyspepsia, bloating, pain abdomen, diarrhoea, constipation etc.) 2. Negative serum anti-transglutaminase (anti-TTg) 3. Negative wheat specific IgE Antibody 4. Normal duodenal biopsy (except increase of intraepithelial lymphocytes (Marsh I) or eosinophilia)
Exclusion criteria
Exclusion criteria: 1. Presence of other disease that can explain persistent GI symptoms (celiac disease, wheat allergy, irritable bowel syndrome, lactose intolerance, diabetes mellitus, hypercalcemia, thyroid disease, biliary/pancreatic causes, H. pylori infection etc.) 2. Patients on self GFD 3. Use of certain medications leading to dyspeptic symptoms 4. Previous history of any GI surgery/GI disorder 5. Major psychiatric disorder 6. Patients who refuse to comply with the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the prevalence of non-celiac wheat sensitivity among patients with functional dyspepsia and IBS like symptomsTimepoint: 9 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the improvement in symptoms in patients with NCWS on GFD To study the improvement in quality of life in patients with NCWS on GFD Timepoint: 9 weeks | — |
Countries
India
Contacts
Public ContactOmesh Goyal
Dayanand Medical College and Hospital
Outcome results
None listed