Improvement in post surgical sequale and postoperative quality of life with dexamethasone impregnated gelfoam after surgical removal of mandibular third molar- A randomized Control Trial

Evaluation of 4mg Dexamethasone solution impregnated in a gelfoam for reduction of post surgical sequelae and improvement in post-operative quality of life after surgical removal of mandibular third molar â?? A randomized control trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/10/037321

Enrollment

Registered

2021-10-14

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: 4MG DEXAMETHASONE SOLUTION IMPREGNATED IN A GELFOAM FOR REDUCTION OF POST SURGICAL SEQUELAE AND IMPROVEMENT IN POST-OPERATIVE QUALITY OF LIFE AFTER SURGICAL REMOVAL OF MANDIBULAR THIRD

Eligibility

Inclusion criteria

Inclusion criteria: Pell& Gregory classification Class I& II, Level A& B and Winters classification of mesioangular type patients reporting to the Department of oral and maxillofacial surgery, Indira Gandhi Institute of Dental Sciences for surgical removal of third molar tooth. • Subjects who are in good physical status ASA level I and level II. • Subjects who could understand and are willing to take part in the study and likely to comply with all study procedures. • Patients without any active foci of infection. • Patient who arenâ??t under any medications.

Exclusion criteria

Exclusion criteria: Refusal to participate in the study Symptoms of Temporomandibular disorders Patient with history of drug allergy to lignocaine, dexamethasone, amoxicillin, ibuprofen and gel foam . Patient who are pregnant and lactating Patients with active infection. Patient under any antibiotics or analgesics coverage. Patient other than Pell & Gregory class-I & II Level A & B. Patients with severe oral manifestations of systemic disease Presence of debilitating systemic illness. Psychologic or psychiatric conditions that could influence response to treatment.

Design outcomes

Primary

Measure	Time frame
Reduction in Post Operative sequale and improvement in post operative quality of life in patients with 4mg dexamethasone gel foam placed inside the socket after extractionTimepoint: Postoperative Day 2, Day 4 and Day &	—

Secondary

Measure	Time frame
Improvement in Function and less post opeartive discomfortTimepoint: 12months	—

Countries

India

Contacts

Public ContactDrR Sathyanarayanan

Indira Gandhi Institute of Dental Sciences,SBV university,Pillayarkuppam,pondicherry

adithyarajam@gmail.com9894027921

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026