It is a study to find out whether Propofol or Ketamine has lower incidence of emergence agitation(It is a dissociated state of consciousness in which children are inconsolable, irritable, uncompromising and /or uncooperative) in children post operatively

PROSPECTIVE RANDOMISED CONTROL STUDY COMPARING THE OCCURRENCE OF POST OPERATIVE EMERGENCE AGITATION WITH THE USE OF SUBHYPNOTIC DOSES OF PROPOFOL OR KETAMINE GIVEN AT THE END OF SURGERY IN CHILDREN OF AGE GROUPS 2 TO 5 YEARS UNDERGOING DAYCARE SUB UMBILICAL SURGERIES

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/10/037300

Enrollment

128

Registered

2021-10-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: propofol: 1 mg/kg INTRAVENOUS ONLY ONCE DURING THE SURGERY Control Intervention1: ketamine: 0.25 mg/kg INTRAVENOUS ONLY ONCE DURING THE SURGERY

Eligibility

Inclusion criteria

Inclusion criteria: 1) CHILDREN WIT INFORMED CONSENT FROM THEIR PARENTS 2) AGE 2 TO 5 YEARS 3) AMERICAN SOCIETY OF ANAESTHESIOLOGISTS 1 4) DAYCARE SUB UMBILICAL SURGERIES

Exclusion criteria

Exclusion criteria: 1) BEHAVIOURAL PROBLEMS 2) DEVELOPMENTAL DELAY 3) SYSTEMIC ILLNESS 4) REACTIVE AIRWAY DISEASE WITH ACUTE EXACERBATION WITHIN 2 WEEKS 5) BLEEDING DISORDERS

Design outcomes

Primary

Measure	Time frame
TO COMPARE RECOVERY CHARACTERS TO COMPARE EMERGENCE AGITATION TO COMPARE POST OP PAIN,NAUSEA AND VOMITINGTimepoint: 6 hrs	—

Secondary

Measure	Time frame
heart rate, blood pressure, respiratory rateTimepoint: 6 hours	—

Countries

India

Contacts

Public ContactDR P AHAMED BEEVI

CHENGALPATTU MEDICAL COLLEGE

ahamedbeevi86@gmail.com9786692410

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026