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Outcomes of corneal neurotization

Clinical outcomes of corneal neurotization using sural nerve graft in neurotrophic keratopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/10/037280
Enrollment
11
Registered
2021-10-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H188- Other specified disorders of cornea Health Condition 2: H188- Other specified disorders of cornea

Interventions

Intervention1: Corneal neurotization using Sural nerve graft: The sural nerve to be used for corneal neurotisation is best identified approximately 2 cm posterior to the lateral malleolus and approxim

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consenting to participate, patients with corneal anaesthesia caused by viral keratitis, damage to the trigeminal nerve following intracranial space occupying lesions such as acoustic neuroma, neurosurgical procedures that damage the ophthalmic division of trigeminal nerve; patients with visually significant neurotrophic keratopathy showing no response to standard medical treatment, patients willing to follow up

Exclusion criteria

Exclusion criteria: Associated lid malposition, incomplete follow up,patients with diabetes,leprosyor peripheral neuropathy,history of previous corneal surgery

Design outcomes

Primary

MeasureTime frame
Quantitative improvement in corneal sensation by crochet bonnet anesthesiometry in the corneaTimepoint: 6 months

Secondary

MeasureTime frame
To study improvement in BCVA, To observe the clarity of cornea as classified by Mackie in neurotrophic keratopathy, to calculate the increase in corneal subbasal nerve fibre plexusTimepoint: 6 months

Countries

India

Contacts

Public ContactDr Aman Kalia

Postgraduate Institute of Medical Education & Research Chandigarh

manusaini1024@gmail.com9999249626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026