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Estimation of Mannose binding lectin in GCF and Serum in Periodontitis patients

Estimation of mannose binding lectin level in gingival crevicular fluid and serum in chronic periodontitis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/10/037260
Enrollment
20
Registered
2021-10-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

None listed

Sponsors

Prerna Tandon
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All the individuals will be included in the study aged 20-60 years and having at least 15 functional teeth. For patients diagnosed with chronic periodontitis there shall be bleeding on probing on at least 30% of sites and 2 teeth in each quadrant. For patients diagnosed with chronic periodontitis there shall be periodontal pocket (�4mm) and clinical attachment loss (�5mm).

Exclusion criteria

Exclusion criteria: Individuals with systemic condition like Diabetes mellitus, Chronic renal disease, hepatitis, HIV. Pregnant women and lactating mothers. Alcoholics and current smokers. Patients who were on analgesic and antibiotic therapy in the last 6 months. Patients who underwent any periodontal therapy in last 6 months

Design outcomes

Primary

MeasureTime frame
To evaluate the impact of the non-surgical periodontal treatment on MBL levels in serum and GCF in chronic periodontitisTimepoint: baseline, 1 month

Secondary

MeasureTime frame
To evaluate the serum and GCF levels of MBL in chronic periodontitis patients before Scaling root planning (SRP). To evaluate the serum and GCF levels of MBL in chronic periodontitis patient after SRP. To evaluate the serum and GCF levels of MBL in chronic periodontitis patients before and after SRP.Timepoint: baseline, 1 month

Countries

India

Contacts

Public ContactDr R G Shiva Manjunath

Institute of Dental Sciences

drmanju75@rediffmail.com8126644491

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026