Health Condition 1: I10- Essential (primary) hypertension Health Condition 2: I10- Essential (primary) hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: FOR CASES: 1.Patient with systolic blood pressure >140mmHg, diastolic blood pressure >90mmHg 2.All patients who are on anti hypertensive treatment 3.Age : 35-75 years FOR CONTROLS: Normotensive subjects of patients relative
Exclusion criteria
Exclusion criteria: 1.Patient with secondary causes of hypertension such as chronic kidney diseases, bilateral renal artery stenosis , coarctation of aorta, congestive cardiac failure. 2.Patient with drug induced nephrotoxic damage. 3.Patient with thyroid dysfunction. 4.Patient with continuous or periodic use of corticosteroid. 5.Patient with severe illness such as malignancy, severe infection, respiratory disease, liver disease. 6.Pregnant women and Women using contraceptive pills.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the Angiotensin II type I receptor gene polymorphism between Essential Hypertensive and normotensive subjects attending to Sir T Hospital Bhavnagar.Timepoint: 1year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess the association of Angiotensin II type I receptor gene polymorphism with family history. 2.To assess the distribution of Angiotensin II type I receptor gene polymorphism according to age, sex and BMI. Timepoint: 1year | — |
Countries
India
Contacts
Government Medical College, Bhavnagar