Health Condition 1: P84- Other problems with newborn
Conditions
Interventions
Intervention1: Prone positioning in preterm neonates receiving non-invasive respiratory support: Participants in this group will be ventilated predominantly in prone position with each session lasting
Sponsors
Dr Suksham Jain
Dr Suksham Jain
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: All neonates born in the hospital who fulfil the following criteria will be enrolled: 1. Gestation age at birth -280/7 to 336/7 weeks 2. Non-invasive ventilation [Continuous positive airway pressure (CPAP) or high flow nasal cannula (HFNC) or non-invasive positive pressure ventilation (NIPPV)] as primary mode of respiratory support, including those extubated within first 6 hours of life or as secondary mode, in whom invasive support has been taken off after first 6 hours of life, but not later than 7 days. 3. Within 6 hours of starting non-invasive ventilation
Exclusion criteria
Exclusion criteria: Exclusion criteria: Neonates with following conditions will be excluded: 1. Neonates extubated from high frequency ventilation after 24 hours 2. Mechanical ventilation for more than 7 days 3. Clinical conditions which make impossible to maintain prone position: a) Intraventricular hemorrhage (IVH) grade III or above before randomization b) Neonatal encephalopathy grade II or above c) Umbilical venous catheter (UVC)/umbilical arterial catheter (UAC) in situ d) Electroencephalographic (EEG) monitoring 4. Major congenital malformation 5. Pulmonary air leaks 6. Persistent pulmonary hypertension of newborn
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total duration of non-invasive respiratory supportTimepoint: At discharge | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Total duration of any oxygen support 2. Failure of non-invasive ventilation 3. Maximum positive inspiratory pressure(PIP) requirement 4. Maximum positive end expiratory pressure (PEEP) requirement 5. Maximum Mean airway pressure requirement 6. Maximum Fio2 requirement 7. Duration of apnoea 8. Frequency of apnoea 9. Duration of NICU stay 10. Duration of hospital stay. 11. Ease of nursing in prone position (Satisfaction on Likertâ??s scale) Timepoint: 1. During hospital stay 2. During NICU stay 3. During NICU stay 4. During NICU stay 5. During NICU stay 6. During NICU stay 7. During NICU stay 8. During NICU stay 9. At discharge from NICU 10. At discharge from hospital 11. Frequently during the NICU stay | — |
Countries
India
Contacts
Public ContactAtul kumar Jha
Government medical college and hospital,
Outcome results
None listed